Last Modified: September 21, 2026
Close-up of a person washing their hands

Keeping poultry houses, coops, and other enclosures clean is one of the best ways to prevent harmful germs from spreading among poultry flocks. Thorough cleaning and disinfecting take time, but the process is vital to keep our flocks healthy.

How To Clean and Disinfect

  • Wear Protective Clothing

    Wear personal protective equipment or clothing and shoes that you only use when caring for your poultry. This includes boot covers or boots that can be disinfected. Change into fresh protective gear between poultry houses or coops.

  • Empty the Enclosure

    Enclosures must be empty for a thorough cleaning. If you have a poultry house, wait until the house is empty to start the cleaning process. If you have a coop or other type of enclosure, move the birds to a separate area before cleaning.

  • Remove Dirt and Debris

    “Dry” clean all areas—brush, scrape, and shovel off manure, feathers, and other materials. Disinfectant won't work through organic matter or caked-on dirt.

  • Wash All Surfaces

    “Wet” clean all surfaces—scrub with water and detergent. Work from top to bottom and back to front. Afterwards, rinse all surfaces carefully with water.

  • Use Disinfectant

    Apply disinfectant per the directions on the label. Be sure to use a disinfectant that has a label that says it’s registered by the U.S. Environmental Protection Agency and is effective against avian influenza and other poultry diseases.

  • Let Everything Dry

    Leave the enclosure empty until it is completely dry. Use fans and/or open doors and windows to help speed the drying process. Wet surfaces can be harmful to poultry.

  • Change and Clean Up

    When you’re done, remove and discard your protective gear. If using dedicated clothing and boots, change clothing and clean and disinfect your boots. Wash hands thoroughly with soap and water.

Learn More About Biosecurity

Protect your birds from wildlife

Keep birds protected against pests and wildlife.
Control what comes in

Set simple rules for visitors, clothes, and shoes near birds.
Back to Biosecurity Basics

Report Sick Birds

If you see signs of illness in your birds, act quickly. Report any sick or dying birds to your State veterinarian or to USDA by calling toll-free 1-866-536-7593 or connecting with your APHIS Area Veterinarian in Charge.